Introduction to Medical Oncology
Targeted Therapy

Targeted Therapy

 

The development of this treatment modality is a major area of cancer drug development.  The focus is on the molecular/genetic changes in malignant cells and supporting surrounding tissue and does not directly target DNA. 

 

 

CLASS

DRUG

 differentiating agents

 retinoids

 angiogenesis inhibitors

 thalidomide, bevacizumab

 monoclonal antibodies

 trastuzumab, rituximab

 alemtuzuma

 EGFR inhibitors

 gefitinib

 Proteosome inhibitors

 bortezomib